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News 2004
First
Norwegian Transgenic Animal Forum at Lysebu, Oslo, 10-11 February
2005
[Announced 30 December 2004]
The first Norwegian
Transgenic Animal Forum will be arranged at Lysebu, Oslo,
10-11 February 2005. |
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CMBN research on
ion channels published in Nature Neuroscience
[Announced 30 December 2004]
CMBN research on the importance of certain ion channels for
learning, memory and epilepsy has been published in Nature
Neuroscience.
Peters HC, Hu H, Pongs O, Storm JF, Isbrandt D (2004) Conditional
transgenic suppression of M channels in mouse brain reveals
functions in neuronal excitability, resonance and behavior.
Nature
Neuroscience, 8, 51-60.
PubMed
| Abstract
| Full
text | PDF |
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Erling
Seeberg has passed away
[Announced 14 December 2004]
We are sad to announce that
Erling Seeberg, preeminent scientist, dear colleague and a
wonderful human being, passed away today, December 14, 2004.
He will be deeply missed.
Erling
Christen Seeberg (1946-2004). Uniforum.
16 December 2004.
Minneord om Erling Seeberg.
17 December 2004.
Obituary
by Vilhelm Bohr in the DNA repair interest group. 17 December
2004.
Obituary:
Erling Christen Seeberg (1946-2004) in DNA
repair. 21 January 2004. |
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BFYS2005
at Randsvangen, 15-17 April 2005
[Announced 11 November 2004]
The Bioinformatics
Forum for Young Scientists 2005 (BFYS2005) will be arranged
at Randsvangen, 15-17 April 2005. |
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Guest
lecture by Jean-Pierre Montmayeur
[Announced 27 October 2004]
Dr. Jean-Pierre Montmayeur, CNRS researcher
in molecular biology/physiology/genetics at the European Centre
of Taste Sciences (CESG) in Dijon, France, will give a guest
lecture on Wednesday 3 November 2004 at 12:15
in new auditorium 13, Domus Medica, with the title:
Development of a genetic method to study olfactory
circuitry in the mouse
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Guest
lecture by Robert Fuchs
[Announced 27 October 2004]
Professor Robert Fuchs from Cancérogénèse
et Mutagénèse Moléculaire et Structurale,
Ecole Supériore de Biotechnologie de Strasbourg (ESBS),
France, will give a guest lecture on Monday 1 November
2004 at 13:00 in Auditorium A3.3067 at Rikshospitalet,
with the title:
Defining the position of the switches between
DNA polymerases during lesion bypass and mutagenesis
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Protein repairs
mRNA and tRNA molecules
[Announced 11 October 2004]
Research
at CMBN have, for the first time, shown that damaged mRNA
and tRNA molecules are repaired just like genomic DNA. The
work was published in the journal Molecular Cell on 8 October
2004 by medical student Rune Ougland (pictured to the right),
Pål Falnes, Rune J Forstrøm, Erling Seeberg and
several international collaborators. It has previously been
shown that bacterial and mammalian AlkB proteins are able
to repair damaged DNA as well as RNA molecules, however it
has now been proved that AlkB proteins are able to fully restore
the biological function of damaged mRNA and tRNA molecules.
For the full story, read the publication in Molecular Cell:
- Ougland R, Zhang C-M, Liiv A, Johansen RF, Seeberg E,
Hou Y-M, Remme J, Falnes PØ (2004) AlkB Restores
the Biological Function of mRNA and tRNA Inactivated by
Chemical Methylation. Molecular
Cell, 16, 107-116.
PubMed
| Abstract
| Full
text | PDF
For more information, read the following media coverage of
the discovery:
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Jahre award
lectures 2004
[Announced 6 October 2004]
The recipients of the Jahre research prize 2004 will give
lectures on Thursday 7 October 2004 at 13.00 to 15.40 in the
new auditorium 13 in Domus Medica, Sognsvannsveien 9. The
prizes will be awarded during a ceremony on Friday 8 October
2004 at 17:20 in Universitetets Aula.
Anders
Jahre's award for medical research 2004 is shared between
Hans E. Krokan, Department of Cancer Research and Molecular
Medicine, Norwegian University of Science and Technology (NTNU)
and Erling C. Seeberg, Centre for Molecular Biology and Neuroscience
(CMBN), Rikshospitalet and the University of Oslo.
The award for young researchers is shared between Patrik
Ernfors, Institutionen för medicinsk biokemi och biofysik
and Claes M. Gustafsson, Institutionen för medicinsk
näringslära, both at Karolinska institutet, Sverige.
About
the Jahre awards
Jahre
lectures programme
Abstracts
Everybody are welcome to the lectures and the ceremony! |
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CMBN booklet
available
[Announced 1 October 2004]
A booklet about CMBN and its research groups is a now available.
Download the PDF
version or contact the CMBN administration for a printed
version. |
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Two
CMBN guest lectures
[Announced 29 September 2004]
CMBN invites to the following two open guest lectures in
connection with the research course:
Prof.
Leena Peltonen from the National Public Health Institute,
Department of Molecular Medicine and Department of Medical
Genetics, University of Helsinki, Finland, will give a guest
lecture on Monday 4 October 2004 at 14:45
in Store Auditorium at Rikshospitalet, with the title:
Impact of modern genomic tools on insight into
neurological diseases. Use of tissue repositories in neurological
research - future possibilities and methodological aspects
Prof. Lars Lannfelt from the Department
of Public Health and Caring Sciences/Geriatrics, Uppsala University,
Sweden, will give a guest lecture on Tuesday 5 October
2004 at 13:45 in Store Auditorium
at Rikshospitalet, with the title:
Genetics, pathophysiology and future treatment
of Alzheimer's disease
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CMBN researcher speaks
on scientific career-making
[Announced 27 September 2004]
CMBN researcher Jon Storm-Mathisen spoke on scientific career-making
at the NatureJobs conference, EuroScience, Stockholm, 26 August
2004.
See: The
joy of the lab. Nature.
9 September 2004. |
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CMBN
research seminar
[Announced 3 September 2004]
Monday 4 - Tuesday 5 October 2004, CMBN research seminar
(forskerkurs) in Store Audiorium, Rikshospitalet:
Recent advances in Molecular Biology and Neuroscience
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Focus on Gaustad Neuroscience Network (GNN)
Deadline for signing on the course: 24 September
2004 to Den norske lægeforening, email koordinatorkontoret.oslo@legeforeningen.no
More information. |
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Anders Jahre's
award for medical research 2004 to Krokan and Seeberg
[Announced 12 August 2004]
Professors Hans E. Krokan and Erling C. Seeberg will be given
Anders Jahre's award for medical research 2004 of NOK 500
000 each for their effort in DNA research. The professors
are awarded for their research showing how the DNA in the
cells are protected and how it is repaired after damage. This
is of major significance in the understanding of ageing and
development of cancer and chronical diseases. Krokan and Seeberg
are associated with the Norwegian University of Science and
Technology (NTNU) in Trondheim and the University of Oslo,
respectively.
See also the articles in Uniforum
and Universitetsavisa.
Congratulations! |
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Guest
lecture by David van Essen
[Announced 6 August 2004]
Dr.
David Van Essen from Washington University at
St. Louis will give a guest lecture on Tuesday 10
August 2004 at 12:30 in the Lunch room, Department
of Anatomy, Domus Medica, with the title:
New approaches to mapping cerebral and cerebellar
cortex in humans, monkeys, mice, and rats
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Research prize
and gold medal to CMBN researchers
[Announced 9 June 2004]
The University of Oslo have decided that Forskningsprisen
2004 (Research Award 2004) is awarded to Professor Jon
Storm-Mathisen, and that His Majesty the King's gold
medal 2004 for the best doctoral thesis at the Faculty of
Medicine is awarded to Mahmood Amiry-Moghaddam.
Both are researchers at CMBN. Congratulations! |
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Publication
in Nature Neuroscience about glutamate release from astrocytes
[Announced 26 May 2004]
Researchers at the Centre for Molecular Biology and Neuroscience
(CMBN), together with researchers at the University of Lausanne
have published a study in Nature Neuroscience that shows that
glutamate is released by regulated exocytosis from astrocytes,
a process previously thought to be occurring only in neurons.
Bezzi P, Gundersen V, Galbete JL, Seifert G, Steinhäuser
C, Pilati E, Volterra A (2004) Astrocytes contain
a vesicular compartment that is competent for regulated exocytosis
of glutamate. Nature
Neuroscience. Published online 23 May 2004.
Abstract
| Full
text | PDF
See also: UiO-forsker
i Nature: Ny forståelse av hjernens signaler. Apollon+
Forskningsnytt på nettet, 26 May 2004. |
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Guest lecture
by David W. Ussery
[Announced 13 May 2004]
Associate
professor David W. Ussery at the Centre for Biological
Sequence Analysis (CBS), Technical University of Denmark (DTU)
will give a guest lecture on Tuesday 22 June 2004
at 13:00 in auditorium A3.3067, Molecular Microbiology, Rikshospitalet,
with the title:
Comparison of 150 Sequenced Bacterial Genomes
Currently there are more than 150 bacterial genomes which
have been fully sequenced. Several different methods for comparison
of these genomes will be discussed, with emphasis on using
our web-based tables for sorting the information (see www.cbs.dtu.dk/services/GenomeAtlas).
The event is co-hosted by the Centre
for Advanced Microbial Science and Technology (CAMST)
and CMBN. |
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CMBN team runs
Holmenkollstafetten in 65 mins 50 secs
[Announced 9 May 2004]
The CMBN team ran Holmenkollstafetten
in 65 minutes 50 seconds and secured a fantastic 23rd
place out of 163 teams in its class. The participants
were very satisfied with the result and celebrated the victory
Saturday night. A silver medal was just one minute away, setting
the goal for next year's team. The team, having number 2120,
was actually the fastest team among the "21xx"-teams
that started last in class 23, and arrived surprisingly early
at the exchange points. Specially designed blue T-shirts with
the CMBN logo had been made for the occasion.
The team:
1.
Katrina Tibbals
2. Liv Kleppa
3. Thomas L Kongsvik
4. Marie Aslaksen
5. Cecilie Narvesen
6. Peder Heyerdahl Utne
7. Vidar Gundersen
8. Janniche Hammer
9. Simen Gylterud
10. Linda Bergersen
11. Tom Tallak Solbu
12. Monica Jenstad
13. Ole Petter Ottersen
14. Arne Klungland
15. Torbjørn Rognes
Supporters: Camilla Haglerød, Svend Davanger and Jon
Storm-Mathisen |
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Publication
in Science about the distribution of glutamate transporters
in the brain
[Announced 1 May 2004]
Researchers at CMBN and co-workers have recently published
the following paper in Science:
Fremeau Jr RT, Kam K, Qureshi T, Johnson J, Copenhagen DR,
Storm-Mathisen J, Chaudhry FA, Nicoll RA, and Edwards RH (2004)
Vesicular Glutamate Transporters 1 and 2 Target to
Functionally Distinct Synaptic Release Sites. Science.
Published online 29 April 2004. Abstract
PDF |
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Guest lecture
by Caleb E. Finch
[Announced 22 April 2004]
Dr
Caleb E. Finch, distinguished gerontologist from
the University of Southern California, will be visiting Norway
from 24 to 27 April. On Monday 26 April 2004
at 14:00 in auditorium A3.3067 at Molecular Microbiology,
Rikshospitalet, he will give a lecture with the title:
Nexus of inflammation, diet, and aging
Dr Finch's visit and lecture will be co-hosted by Prof. Erling
Seeberg, Centre for Molecular Biology and Neuroscience, Oslo,
and Prof. Stig W. Omholt, CIGENE.
Inflammatory processes are emerging as fundamental to aging
and
major diseases of aging. Many of the same drugs with anti-inflammatory
activities that reduce the risk of vascular events also reduce
the risk of
certain cancers, and possibly also Alzheimer disease. Inflammation
and the incidence of these diseases may also be modulated
by diet. The evolution of longevity may involve genes that
regulate inflammatory responses. This nexus of inflammation,
diet, and aging will be discussed with examples from human
aging and animal models.
Dr Finch is professor of molecular biology and gerontology
at the USC School of Gerontology. His main interest is the
study of genomic controls of mammalian development and aging.
He has authored three books: Longevity, Senescence, and the
Genome (1990); Aging: A Natural History (1995, with R. Ricklefs);
and Chance, Development, and Aging (2000, with TBL Kirkwood).
In 350 reports and reviews since 1969, Finch has led several
developments in the fields of the neuroendocrinology and pharmacology
of normal aging and Alzheimer disease, and in the biodemography
of aging.
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Cerebellum
and Disease Models - Workshop
[Announced 21 April 2004]
The Cerebellum
and Disease Models Workshop takes place at the Norwegian
Academy of Sciences in Oslo on 27 May 2004. A few places are
still available. For inqueries about registration, contact:
Brita Engebakken by email to brita.engebakken@medisin.uio.no. |
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Guest lecture
by Kathleen J. Sweadner
[Announced 14 April 2004]
Dr. Kathleen J. Sweadner, Associate Professor
at Harvard Medical School and Associate Neurobiologist at
Massachusetts General Hospital, will give a guest lecture
on Monday 19 April 2004 at 14.15 in the new auditorium
13, Domus Medica, with the title:
FXYD proteins: Single-span membrane protein
regulators of Na, K-ATPase
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Guest lectures
by Claudio Franceschi
[Announced 1 March 2004]
Prof. Claudio Franceschi, University
of Bologna, Italy, will give a guest lecture on Thursday
4 March 2004 at 14:00 in auditorium A3.3067 at Molecular
Microbiology, Rikshospitalet, with the title:
Immunology and genetics of ageing and
longevity in humans
Prof. Franceschi will also give a
guest lecture on Wednesday 3 March 2004
at 11:15-12:00 in auditorium U338 in "Urbygningen"
at the Agricultural University of Norway at Ås,
with the title:
The immune system as a complex system:
mathematical models of immunosenescence
More... |
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Guest lectures
by Harold Kimelberg and
Jean-Antoine Girault
[Announced 1 March 2004]
On Wednesday 17 March 2004, Dr. Harold Kimelberg, Neural
and Vascular Biology Theme, Ordway Research Institute, will
give a guest lecture with the title: Neuroprotection after
acute brain injury aimed at inhibition of cellular edema and
its consequences.
On Thursday 18 March 2004, Prof. Jean-Antoine Girault, Directur,
Transduction du Signal et Plasticité dans le Systéme
Nerveux, INSERM, will give a guest lecture with the title:
Molecular Development of Nodes of Ranvier.
More... |
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Updated program
and extended application deadline for the research seminar
on genome instability and neurologic disease
[Announced 27 February 2004]
The program for the research seminar (forskerkurs) on genome
instability and neurologic disease on 22 and 23 April 2004 has
been updated. The application deadline has been extended to
1 April 2004.
More... |
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Guest
lecture by Michel Khrestchatisky
[Announced
15 February 2004]
Monday 16 February 2004 at 14.00, Directeur
Michel Khrestchatisky at CNRS, Neurobiologie des Interactions
Cellulaires et Neurophysiopathologie will give a guest lecture
in new auditorium 13, Domus Medica, with the title:
The Matrix Metalloproteinases (MMPs) and their
endogenous inhibitors (TIMPs) in plasticity and pathologies
of the central nervous system
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Minisymposium:
Oxidative DNA damage and repair: Role in cancer and ageing
[Announced 9 February 2004]
Minisymposium to be held on Thursday 12 February 2004 at
14.00, in auditorium A3.3067, Rikshospitalet.
Details |
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Two PhD studentships
in bioinformatics available
[Announced 5 February 2004]
CMBN announces the availability of two PhD studentships in
bioinformatics. For details, visit the jobs
page. |
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Postdoctoral and PhD
position available
[Announced 28 January 2004]
CMBN announces the availability of a postdoctoral and a PhD
position. For details, visit the jobs
page. |
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Guest lectures
[Announced 20 January 2004]
On Tuesday 20 January 2004, Dr. Nicholas Luscombe,
Yale University, will give a guest lecture with the title
Transcription regulation: a genomic network.
On Wednesday 21 January 2004, Dr Iacob Matthiesen,
Inovio AS, will give a guest lecture with the title Enabling
gene therapy and DNA vaccine applications with a new method
for gene delivery to skeletal muscles.
More... |
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Research seminar
on genome instability and neurologic disease
[Announced 11 January 2004]
CMBN announces a research seminar (forskerkurs) on genome instability
and neurologic disease on 22 and 23 April 2004.
More... |
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Guest lecture
by Stig Omholt
[Announced 5 January 2004]
Monday 26 January 2004 at 13.00, guest lecture
in the new auditorium 13, Domus Medica:
Professor Stig Omholt, Agricultural
University of Norway, will give a lecture with the title:
Control of ageing - lessons from bees, flies,
worms and mice
Welcome! |
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