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News 2010

CMBN collaborative study on Huntington's disease published in PLoS Genetics
Announced 9 December 2010

CMBN scientists have recently published a paper in the journal PLoS Genetics on two modes of expansion of CAG repeats in Huntington's disease mice.

Møllersen L, Rowe AD, Larsen E, Rognes T, Klungland A
Continuous and periodic expansion of CAG repeats in Huntington’s disease R6/1 mice
PLoS Genet, 6 (12), e1001242



CAG repeat length distribution

Publication in Blood by CMBN scientists
Announced 24 August 2010

CMBN scientists have recently published a paper in the journal Blood on degradation of an important oncoprotein in leukemia. The project is a collaboration between the research groups of Stig Ove Bøe and Anne Simonsen.

Isakson P, Bjørås M, Bøe SO, Simonsen A
Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein
Blood (in press)

The project is featured as the Monthly research project by the Norwegian Cancer Society:

Celler spiser kreftfremkallende komponenter


Stig Ove Bøe, Pauline Isakson & Anne Simonsen

Publication in PLoS Pathogens by CMBN scientists
Announced 24 August 2010

CMBN scientists have recently published a paper on the evolution of pathogenic Neisseria in the journal PLoS Pathogens:

Aspholm M, Aas FE, Harrison OB, Quinn D, Vik Å, Viburiene R, Tønjum T, Moir J, Maiden MCJ, Koomey M (2010)
Structural Alterations in a Component of Cytochrome c Oxidase and Molecular Evolution of Pathogenic Neisseria in Humans
PLoS Pathogens, 6 (8), e1001055

The paper is highlighted as Featured Research in PLoS Pathogens:

Aspholm, Aas and colleagues describe two successive alterations in a single gene that can be linked first to all species within the genus Neisseria and then the species N. meningitidis. Their findings provide a dramatic example of how rare changes in core metabolic proteins can be connected to significant macroevolutionary shifts and have significant implications for the evolution of related bacterial species within a single host.


Nansen Neuroscience Network inauguration
Announced 10 May 2010

Welcome to the inauguration meeting of the Nansen Neuroscience Network!

Tuesday 11 May 2010 at 1400
In the Art hall, Mezzanine, Radisson Blu Plaza Hotel, Sonja Henies Plass 3, Oslo


Moderator Jon Storm-Mathisen, Professor, Dep. of Anatomy, University of Oslo

Programme as PDF

1400   Opening
Minister of Health, Anne-Grete Strøm-Erichsen
1410   Innovation through industrial – academic collaboration
Gunn Ovesen, President and CEO of Innovation Norway
1420   Presentation of Nansen Neuroscience Network; a new opportunity for science and industry
Stein Lorentzen-Lund, Project Director, NNN
1435   The clinical challenges related to the brain
Gunnar Bovim, CEO, Helse Midt-Norge
1445   The industrial expectations for collaboration with academia
Karita Bekkemellem, CEO LMI
1505   The industry perspective; what contributions have been made in neuroscience andwhat is to come. The market needs and business opportunities ahead
Eva Dencher Vansvik, Medical Director Neuroscience, AstraZeneca
1525   Science and networking
Ole Petter Ottersen, Rector, University of Oslo
1545   Panel discussion
Moderated by Ole Jørgen Marvik, Sector Head Health and Life Sciences, Innovation Norway
1630   Closing, networking and refreshments
1700   Adjourn
Fridtjof Nansen
CMBN annual report 2009
Announced 21 April 2010

CMBN annual report 2009 The CMBN annual report 2009 is now available.
Leena Peltonen has passed away
Announced 14 March 2010

It is with deep sadness CMBN received the message that Leena Peltonen, Coordinator of the NCoEDG program and NordForsk Sequencing project, passed away on March 11, 2010, at home in Helsinki.

Leena has been an inspiration to scientists worldwide and will be greatly missed.

If you would like to express your condolences for Leena, you can leave your message on the FIMM website.

Publication by CMBN scientist in Science
Announced 12 January 2010

CMBN scientist Hua Hu has recently published a paper on signals in interneuron dendrites in Science:

Hu H, Martina M, Jonas P (2010)
Dendritic mechanisms underlying rapid synaptic activation of fast-spiking hippocampal interneurons
Science, 327 (5961), 52-8
PubMed 19965717



Centre for Molecular Biology and Neuroscience (CMBN)
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