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Publications 2011

  1. Abu Hossain S, Chaudhry FA, Zahedi K, Siddiqui F, Amlal H (2011)
    Cellular and molecular basis of increased ammoniagenesis in potassium deprivation
    Am J Physiol Renal Physiol, 301 (5), F969-78
    PubMed 21795646
  2. Ahlgren H, Henjum K, Ottersen OP, Rundén-Pran E (2011)
    Validation of organotypical hippocampal slice cultures as an ex vivo model of brain ischemia: different roles of NMDA receptors in cell death signalling after exposure to NMDA or oxygen and glucose deprivation
    Cell Tissue Res, 345 (3), 329-41
    PubMed 21874291
  3. Alvestad S, Hammer J, Qu H, Håberg A, Ottersen OP, Sonnewald U (2011)
    Reduced astrocytic contribution to the turnover of glutamate, glutamine, and GABA characterizes the latent phase in the kainate model of temporal lobe epilepsy
    J Cereb Blood Flow Metab, 31 (8), 1675-86
    PubMed 21522161
  4. Arczewska KD, Baumeier C, Kassahun H, Sengupta T, Bjørås M, Kuśmierek JT, Nilsen H (2011)
    Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability
    DNA Repair (Amst), 10 (2), 176-87
    PubMed 21111690
  5. Belova NV, Dalhus B, Girichev GV, Giricheva NI, Haaland A, Kuzmima NP, Zhukova TA (2011)
    The molecular structure of tris-2,2,6,6-tetramethyl-heptane-3,5-dione aluminium: gas-phase electron diffraction, quantum chemical calculations and X-ray crystallography
    Struct. Chem., 22 (2), 393-399
  6. Benam AV, Lång E, Alfsnes K, Fleckenstein B, Rowe AD, Hovland E, Ambur OH, Frye SA, Tønjum T (2011)
    Structure-function relationships of the competence lipoprotein ComL and SSB in meningococcal transformation
    Microbiology, 157 (Pt 5), 1329-42
    PubMed 21330432
  7. Benfenati V, Caprini M, Dovizio M, Mylonakou MN, Ferroni S, Ottersen OP, Amiry-Moghaddam M (2011)
    An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes
    Proc Natl Acad Sci U S A, 108 (6), 2563-8
    PubMed 21262839
  8. Bergersen LH, Sander M, Storm-Mathisen J (2011)
    What the nose knows, what the eyes see, how we feel, how we learn, how we understand motor acts, why "YY" is essential for ion transport, how epigenetics meet neurobiology in Rett syndrome: seven topics at the 2010 Kavli Prize Symposium on Neuroscience
    Neuroscience, 190, 1-11
    PubMed 21624437
  9. Bolle E, Rissi M, Bjaalie JG, Buskenes JI, Dorholt O, Rohne O, Skretting A, Stapnes S (2011)
    COMPET - high resolution and high sensitivity PET scanner with novel readout concept: Setup and simulations
    Nucl. Instrum. Methods Phys. Res. Sect. A-Accel. Spectrom. Dect. Assoc. Equip., 648 S1, S93-S95
  10. Bøhle LA, Riaz T, Egge-Jacobsen W, Skaugen M, Busk ØL, Eijsink VG, Mathiesen G (2011)
    Identification of surface proteins in Enterococcus faecalis V583
    BMC Genomics, 12, 135
    PubMed 21362161
  11. Børud B, Viburiene R, Hartley MD, Paulsen BS, Egge-Jacobsen W, Imperiali B, Koomey M (2011)
    Genetic and molecular analyses reveal an evolutionary trajectory for glycan synthesis in a bacterial protein glycosylation system
    Proc Natl Acad Sci U S A, 108 (23), 9643-8
    PubMed 21606362
  12. Coello C, Hjornevik T, Courivaud F, Willoch F (2011)
    Anatomical standardization of small animal brain FDG-PET images using synthetic functional template: experimental comparison with anatomical template
    J Neurosci Methods, 199 (1), 166-72
    PubMed 21550366
  13. Dalhus B, Forsbring M, Helle IH, Vik ES, Forstrøm RJ, Backe PH, Alseth I, Bjørås M (2011)
    Separation-of-function mutants unravel the dual-reaction mode of human 8-oxoguanine DNA glycosylase
    Structure, 19 (1), 117-27
    PubMed 21220122
  14. Egge-Jacobsen W, Salomonsson EN, Aas FE, Forslund AL, Winther-Larsen HC, Maier J, Macellaro A, Kuoppa K, Oyston PC, Titball RW, Thomas RM, Forsberg Å, Prior JL, Koomey M (2011)
    O-linked glycosylation of the PilA pilin protein of Francisella tularensis: identification of the endogenous protein-targeting oligosaccharyltransferase and characterization of the native oligosaccharide
    J Bacteriol, 193 (19), 5487-97
    PubMed 21804002
  15. Fusser M, Nesse GJ, Khobta A, Xia N, Li H, Klungland A, Epe B (2011)
    Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol
    Carcinogenesis, 32 (1), 80-5
    PubMed 21062970
  16. Gammelsaeter R, Coppola T, Marcaggi P, Storm-Mathisen J, Chaudhry FA, Attwell D, Regazzi R, Gundersen V (2011)
    A role for glutamate transporters in the regulation of insulin secretion
    PLoS One, 6 (8), e22960
    PubMed 21853059
  17. Haj-Yasein NN, Jensen V, Vindedal GF, Gundersen GA, Klungland A, Ottersen OP, Hvalby O, Nagelhus EA (2011)
    Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human Kir4.1 gene (KCNJ10)
    Glia, 59 (11), 1635-42
    PubMed 21748805
  18. Haj-Yasein NN, Vindedal GF, Eilert-Olsen M, Gundersen GA, Skare Ø, Laake P, Klungland A, Thorén AE, Burkhardt JM, Ottersen OP, Nagelhus EA (2011)
    Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet
    Proc Natl Acad Sci U S A, 108 (43), 17815-20
    PubMed 21990350
  19. Hartley MD, Morrison MJ, Aas FE, Børud B, Koomey M, Imperiali B (2011)
    Biochemical characterization of the O-linked glycosylation pathway in Neisseria gonorrhoeae responsible for biosynthesis of protein glycans containing N,N'-diacetylbacillosamine
    Biochemistry, 50 (22), 4936-48
    PubMed 21542610
  20. Helm PJ, Ottersen OP (2011)
    Proposal of a new method to measure FRET quantitatively in living or fixed biomedical specimens on a laser microscope
    PROC SPIE, 7903, 790331
  21. Hereng TH, Elgstøen KB, Cederkvist FH, Eide L, Jahnsen T, Skålhegg BS, Rosendal KR (2011)
    Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa
    Hum Reprod, 26 (12), 3249-63
    PubMed 21946930
  22. Holla ØL, Cameron J, Tveten K, Strøm TB, Berge KE, Laerdahl JK, Leren TP (2011)
    Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors
    J Lipid Res, 52 (10), 1787-94
    PubMed 21771976
  23. Holla ØL, Laerdahl JK, Strøm TB, Tveten K, Cameron J, Berge KE, Leren TP (2011)
    Removal of acidic residues of the prodomain of PCSK9 increases its activity towards the LDL receptor
    Biochem Biophys Res Commun, 406 (2), 234-8
    PubMed 21324305
  24. Hussain S, Davanger S (2011)
    The discovery of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex and the molecular regulation of synaptic vesicle transmitter release: the 2010 Kavli Prize in neuroscience
    Neuroscience, 190, 12-20
    PubMed 21641968
  25. Irvine EE, Drinkwater L, Radwanska K, Al-Qassab H, Smith MA, O'Brien M, Kielar C, Choudhury AI, Krauss S, Cooper JD, Withers DJ, Giese KP (2011)
    Insulin receptor substrate 2 is a negative regulator of memory formation
    Learn Mem, 18 (6), 375-83
    PubMed 21597043
  26. Jacobsen Ø, Maekawa H, Ge NH, Görbitz CH, Rongved P, Ottersen OP, Amiry-Moghaddam M, Klaveness J (2011)
    Stapling of a 3(10)-helix with click chemistry
    J Org Chem, 76 (5), 1228-38
    PubMed 21275402
  27. Jing Y, Machon O, Hampl A, Dvorak P, Xing Y, Krauss S (2011)
    In vitro differentiation of mouse embryonic stem cells into neurons of the dorsal forebrain
    Cell Mol Neurobiol, 31 (5), 715-27
    PubMed 21424551
  28. Johnsen L, Flåtten I, Morigen, Dalhus B, Bjørås M, Waldminghaus T, Skarstad K (2011)
    The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
    Mol Microbiol, 79 (2), 433-46
    PubMed 21219462
  29. Kasper M, Jaks V, Are A, Bergström Å, Schwäger A, Svärd J, Teglund S, Barker N, Toftgård R (2011)
    Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes
    Proc Natl Acad Sci U S A, 108 (10), 4099-104
    PubMed 21321199
  30. Kjonigsen LJ, Leergaard TB, Witter MP, Bjaalie JG (2011)
    Digital atlas of anatomical subdivisions and boundaries of the rat hippocampal region
    Front Neuroinform, 5, 2
    PubMed 21519393
  31. Korvald H, Mølstad Moe AM, Cederkvist FH, Thiede B, Laerdahl JK, Bjørås M, Alseth I (2011)
    Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones
    PLoS One, 6 (9), e25188
    PubMed 21949882
  32. Kaarbø M, Ager-Wick E, Osenbroch PØ, Kilander A, Skinnes R, Müller F, Eide L (2011)
    Human cytomegalovirus infection increases mitochondrial biogenesis
    Mitochondrion, 11 (6), 935-45
    PubMed 21907833
  33. Laerdahl JK, Korvald H, Nilsen L, Dahl-Michelsen K, Rognes T, Bjørås M, Alseth I (2011)
    Schizosaccharomyces pombe encodes a mutated AP endonuclease 1
    DNA Repair (Amst), 10 (3), 296-305
    PubMed 21193357
  34. Larsson M, Broman J (2011)
    Synaptic plasticity and pain: role of ionotropic glutamate receptors
    Neuroscientist, 17 (3), 256-73
    PubMed 20360599
  35. Larsson M, Morland C, Poblete-Naredo I, Biber J, Danbolt NC, Gundersen V (2011)
    The sodium-dependent inorganic phosphate transporter SLC34A1 (NaPi-IIa) is not localized in the mouse brain: a case of tissue-specific antigenic cross-reactivity
    J Histochem Cytochem, 59 (9), 807-12
    PubMed 21606201
  36. Lauritzen F, de Lanerolle NC, Lee TS, Spencer DD, Kim JH, Bergersen LH, Eid T (2011)
    Monocarboxylate transporter 1 is deficient on microvessels in the human epileptogenic hippocampus
    Neurobiol Dis, 41 (2), 577-84
    PubMed 21081165
  37. Lauritzen KH, Cheng C, Wiksen H, Bergersen LH, Klungland A (2011)
    Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses
    DNA Repair (Amst), 10 (6), 639-53
    PubMed 21550321
  38. Lauritzen KH, Dalhus B, Storm JF, Bjørås M, Klungland A (2011)
    Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond
    Mech Ageing Dev, 132 (8-9), 424-8
    PubMed 21354441
  39. Lehre AC, Rowley NM, Zhou Y, Holmseth S, Guo C, Holen T, Hua R, Laake P, Olofsson AM, Poblete-Naredo I, Rusakov DA, Madsen KK, Clausen RP, Schousboe A, White HS, Danbolt NC (2011)
    Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice
    Epilepsy Res, 95 (1-2), 70-81
    PubMed 21459558
  40. Lillenes MS, Espeseth T, Støen M, Lundervold AJ, Frye SA, Rootwelt H, Reinvang I, Tønjum T (2011)
    DNA base excision repair gene polymorphisms modulate human cognitive performance and decline during normal life span
    Mech Ageing Dev, 132 (8-9), 449-58
    PubMed 21884718
  41. Medin T, Owe SG, Rinholm JE, Larsson M, Sagvolden T, Storm-Mathisen J, Bergersen LH (2011)
    Dopamine D5 receptors are localized at asymmetric synapses in the rat hippocampus
    Neuroscience, 192, 164-71
    PubMed 21749912
  42. Melum E, Franke A, Schramm C, Weismüller TJ, Gotthardt DN, Offner FA, Juran BD, Laerdahl JK, Labi V, Björnsson E, Weersma RK, Henckaerts L, Teufel A, Rust C, Ellinghaus E, Balschun T, Boberg KM, Ellinghaus D, Bergquist A, Sauer P, Ryu E, Hov JR, Wedemeyer J, Lindkvist B, Wittig M et al. (2011)
    Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
    Nat Genet, 43 (1), 17-9
    PubMed 21151127
  43. Moen MN, Knævelsrud I, Haugland GT, Grøsvik K, Birkeland NK, Klungland A, Bjelland S (2011)
    Uracil-DNA glycosylase of Thermoplasma acidophilum directs long-patch base excision repair, which is promoted by deoxynucleoside triphosphates and ATP/ADP, into short-patch repair
    J Bacteriol, 193 (17), 4495-508
    PubMed 21665970
  44. Myhre HA, Haug Dorenberg D, Kristiansen KI, Rollag H, Leivestad T, Asberg A, Hartmann A (2011)
    Incidence and outcomes of ganciclovir-resistant cytomegalovirus infections in 1244 kidney transplant recipients
    Transplantation, 92 (2), 217-23
    PubMed 21685829
  45. Nissen-Meyer LS, Popescu MC, Hamdani el H, Chaudhry FA (2011)
    Protein kinase C-mediated phosphorylation of a single serine residue on the rat glial glutamine transporter SN1 governs its membrane trafficking
    J Neurosci, 31 (17), 6565-75
    PubMed 21525297
  46. Odeh F, Leergaard TB, Boy J, Schmidt T, Riess O, Bjaalie JG (2011)
    Atlas of transgenic Tet-Off Ca2+/calmodulin-dependent protein kinase II and prion protein promoter activity in the mouse brain
    Neuroimage, 54 (4), 2603-11
    PubMed 21093594
  47. Ricanek P, Rydning A, Vatn MH, Tonjum T (2011)
    Considered "negative" for MAP, these results would be very "positive" for tuberculoid leprosy Reply
    J. Crohns Colitis, 5 (4), 374
  48. Rinholm JE, Hamilton NB, Kessaris N, Richardson WD, Bergersen LH, Attwell D (2011)
    Regulation of oligodendrocyte development and myelination by glucose and lactate
    J Neurosci, 31 (2), 538-48
    PubMed 21228163
  49. Robertson AB, Dahl JA, Vågbø CB, Tripathi P, Krokan HE, Klungland A (2011)
    A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA
    Nucleic Acids Res, 39 (8), e55
    PubMed 21300643
  50. Robertson J, Robertson AB, Klungland A (2011)
    The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression
    Biochem Biophys Res Commun, 411 (1), 40-3
    PubMed 21703242
  51. Rognes T (2011)
    Faster Smith-Waterman database searches with inter-sequence SIMD parallelisation
    BMC Bioinformatics, 12, 221
    PubMed 21631914
  52. Sejersted Y, Hildrestrand GA, Kunke D, Rolseth V, Krokeide SZ, Neurauter CG, Suganthan R, Atneosen-Åsegg M, Fleming AM, Saugstad OD, Burrows CJ, Luna L, Bjørås M (2011)
    Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
    Proc Natl Acad Sci U S A, 108 (46), 18802-7
    PubMed 22065741
  53. Stahl K, Mylonakou MN, Skare Ø, Amiry-Moghaddam M, Torp R (2011)
    Cytoprotective effects of growth factors: BDNF more potent than GDNF in an organotypic culture model of Parkinson's disease
    Brain Res, 1378, 105-18
    PubMed 21236244
  54. Strand MF, Wilson SR, Dembinski JL, Holsworth DD, Khvat A, Okun I, Petersen D, Krauss S (2011)
    A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model
    PLoS One, 6 (6), e19904
    PubMed 21698280
  55. Strømme P, Dobrenis K, Sillitoe RV, Gulinello M, Ali NF, Davidson C, Micsenyi MC, Stephney G, Ellevog L, Klungland A, Walkley SU (2011)
    X-linked Angelman-like syndrome caused by Slc9a6 knockout in mice exhibits evidence of endosomal-lysosomal dysfunction
    Brain, 134 (Pt 11), 3369-83
    PubMed 21964919
  56. Thrane AS, Rappold PM, Fujita T, Torres A, Bekar LK, Takano T, Peng W, Wang F, Rangroo Thrane V, Enger R, Haj-Yasein NN, Skare Ø, Holen T, Klungland A, Ottersen OP, Nedergaard M, Nagelhus EA (2011)
    Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema
    Proc Natl Acad Sci U S A, 108 (2), 846-51
    PubMed 21187412
  57. Toft M, Lilleeng B, Ramm-Pettersen J, Skogseid IM, Gundersen V, Gerdts R, Pedersen L, Skjelland M, Røste GK, Dietrichs E (2011)
    Long-term efficacy and mortality in Parkinson's disease patients treated with subthalamic stimulation
    Mov Disord, 26 (10), 1931-4
    PubMed 21656853
  58. Tønjum T, Koomey M (2011)
    Kiss and run - phosphoglycerol modifications of N. Meningitidis pili mediate detachment
    Front Microbiol, 2, 82
    PubMed 21747798
  59. van den Born E, Vågbø CB, Songe-Møller L, Leihne V, Lien GF, Leszczynska G, Malkiewicz A, Krokan HE, Kirpekar F, Klungland A, Falnes PØ (2011)
    ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA
    Nat Commun, 2, 172
    PubMed 21285950
  60. Veraart J, Leergaard TB, Antonsen BT, Van Hecke W, Blockx I, Jeurissen B, Jiang Y, Van der Linden A, Johnson GA, Verhoye M, Sijbers J (2011)
    Population-averaged diffusion tensor imaging atlas of the Sprague Dawley rat brain
    Neuroimage, 58 (4), 975-83
    PubMed 21749925
  61. Wang W, Esbensen Y, Kunke D, Suganthan R, Rachek L, Bjørås M, Eide L (2011)
    Mitochondrial DNA damage level determines neural stem cell differentiation fate
    J Neurosci, 31 (26), 9746-51
    PubMed 21715639
  62. Waaler J, Machon O, von Kries JP, Wilson SR, Lundenes E, Wedlich D, Gradl D, Paulsen JE, Machonova O, Dembinski JL, Dinh H, Krauss S (2011)
    Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth
    Cancer Res, 71 (1), 197-205
    PubMed 21199802
  63. Yang J, Lunde LK, Nuntagij P, Oguchi T, Camassa LM, Nilsson LN, Lannfelt L, Xu Y, Amiry-Moghaddam M, Ottersen OP, Torp R (2011)
    Loss of astrocyte polarization in the tg-ArcSwe mouse model of Alzheimer's disease
    J Alzheimers Dis, 27 (4), 711-22
    PubMed 21891870
  64. Yang M, Aamodt RM, Dalhus B, Balasingham S, Helle I, Andersen P, Tønjum T, Alseth I, Rognes T, Bjørås M (2011)
    The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage
    DNA Repair (Amst), 10 (6), 595-602
    PubMed 21570366
  65. Zakiewicz IM, van Dongen YC, Leergaard TB, Bjaalie JG (2011)
    Workflow and atlas system for brain-wide mapping of axonal connectivity in rat
    PLoS One, 6 (8), e22669
    PubMed 21829640
  66. Zhang Y, Reckow S, Webhofer C, Boehme M, Gormanns P, Egge-Jacobsen WM, Turck CW (2011)
    Proteome scale turnover analysis in live animals using stable isotope metabolic labeling
    Anal Chem, 83 (5), 1665-72
    PubMed 21314131
  67. Zimmermann C, Chymkowitch P, Eldholm V, Putnam CD, Lindvall JM, Omerzu M, Bjørås M, Kolodner RD, Enserink JM (2011)
    A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression
    Proc Natl Acad Sci U S A, 108 (46), 18748-53
    PubMed 22042866

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