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The Centre for Molecular Biology and Neuroscience (CMBN) (Senter for molekylærbiologi og nevrovitenskap) is a Norwegian Centre of Excellence at the University of Oslo and Rikshospitalet, Oslo University Hospital. CMBN shall take on a leading role in elucidating the role of DNA repair and genome maintenance mechanisms in preventing neurological disease and brain ageing.

Recent news and upcoming events
Annual Kavli Lecture Trondheim 2010: Mark Bear
Announced 13 January 2010

Kavli Lecture Trondheim 2010

 

CMBN is pleased to announce the Annual Kavli Lecture Trondheim 2010

A cure for fragile X? Fulfilling the promise of molecular medicine in a developmental brain disorder

Dr. Mark Bear is a Howard Hughes Medical Institute Investigator and is the Picower Professor of Neuroscience at the Picower Institute for Learning and Memory and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology.

Thursday 18 March 2010 at 1800

The Student Society Building, Trondheim

Publication by CMBN scientist in Science
Announced 12 January 2010

CMBN scientist Hua Hu has recently published a paper on signals in interneuron dendrites in Science:

Hu H, Martina M, Jonas P (2010)
Dendritic mechanisms underlying rapid synaptic activation of fast-spiking hippocampal interneurons
Science, 327 (5961), 52-8
PubMed 19965717

 

Dendrite

Medinnova Idea Prize 2009 awarded to CMBN scientists for new antibiotic
Announced 20 November 2009

Medinnova Idea Prize 2009

CMBN scientists Magnar Bjørås, James Booth, Ragnhild Weel‐Sneve and Knut Ivan Kristiansen have received Medinnova's Idea Prize for 2009. The scientists are developing a new drug that kills bacteria.

The prize is awarded every year for the best idea with commercial potential from employees in the health region.

Press release from Medinnova

Committee's report

Medinnovas Idépris til forskning på nytt bakteriedrepende legemiddel
Aktuelt fra Rikshospitalet, 20 November 2009

CMBN scientist awarded group leader position in Molecular Medicine
Announced 19 November 2009

Erlend A. Nagelhus   Erlend A. Nagelhus, MD, PhD, has started as group Leader at the Centre for Molecular Medicine Norway (NCMM), the Nordic EMBL partnership, University of Oslo.

He will run his research group at the Institute of Basic Medical Sciences, in affiliation with CMBN, and be responsible for the neuroimaging activity in Letten Research Centre. Nagelhus' group will focus on roles of aquaporins in brain fluid and vascular dynamics.


Media coverage
Tone Tønjum   Forsker på cocktail mot aldring
VG (print edition, p. 22)
26 February 2010
Elisabeth Larsen

Lovende stamceller
Kronikk av Elisabeth Larsen (PhD, CMBN & Rikshospitalet)
Aftenposten
23 January 2010


Bakterier endrer synet på sex
forskning.no
23 October 2009
Ole Herman Ambur

Bakterier endrer oppfatningen om sex
Apollon
19 October 2009
Nobelprisen i medisin for oppdagelsen av telomerer (MP3)
(Intervju med Magnar Bjørås)
Verdt å vite, NRK Radio P2
6 October 2009
Ida Rosnes   Ryggejente kan knekke kreftkode
Moss Avis
3 August 2009
Åshild Vik   Gonoré, en søt bakterie
Uniforum
20 August 2009
Håpløst urealistisk holdning? Debattinnlegg av Jon Storm-Mathisen
Aftenposten
17 August 2009
Hjernens mysterier   Hjernens mysterier (video)
Lørdagsmag., Nyhetene, TV2
21 March 2009

More media coverage...

Latest publications

Solbu TT, Bjørkmo M, Berghuis P, Harkany T, Chaudhry FA (2010)
SAT1, A Glutamine Transporter, is Preferentially Expressed in GABAergic Neurons
Front Neuroanat, 4, 1
PubMed 20161990

Dahl JA, Reiner AH, Klungland A, Wakayama T, Collas P (2010)
Histone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos
PLoS One, 5 (2), e9150
PubMed 20161773

Pechstein A, Bacetic J, Vahedi-Faridi A, Gromova K, Sundborger A, Tomlin N, Krainer G, Vorontsova O, Schäfer JG, Owe SG, Cousin MA, Saenger W, Shupliakov O, Haucke V (2010)
Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2
Proc Natl Acad Sci U S A, 107 (9), 4206-11
PubMed 20160082

Schoultz BW, Hjornevik T, Willoch F, Marton J, Noda A, Murakami Y, Miyoshi S, Nishimura S, Arstad E, Drzezga A, Matsunari I, Henriksen G
Evaluation of the kappa-opioid receptor-selective tracer [(11)C]GR103545 in awake rhesus macaques
Eur J Nucl Med Mol Imaging (in press)
PubMed 20157708

Nemani VM, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, Chaudhry FA, Nicoll RA, Edwards RH (2010)
Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis
Neuron, 65 (1), 66-79
PubMed 20152114

Songe-Møller L, van den Born E, Leihne V, Vågbø CB, Kristoffersen T, Krokan HE, Kirpekar F, Falnes PO, Klungland A
Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding
Mol Cell Biol (in press)
PubMed 20123966

Lagesen K, Ussery DW, Wassenaar TM (2010)
Genome update: the 1000th genome - a cautionary tale
Microbiology, 156 (Pt 3), 603-8
PubMed 20093288

Nörenberg A, Hu H, Vida I, Bartos M, Jonas P (2010)
Distinct nonuniform cable properties optimize rapid and efficient activation of fast-spiking GABAergic interneurons
Proc Natl Acad Sci U S A, 107 (2), 894-9
PubMed 20080772

Glover JC, Boulland JL, Halasi G, Kasumacic N (2009)
Chimeric animal models in human stem cell biology
ILAR J, 51 (1), 62-73
PubMed 20075498

Lauritzen KH, Moldestad O, Eide L, Carlsen H, Nesse G, Storm JF, Mansuy IM, Bergersen LH, Klungland A (2010)
Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior
Mol Cell Biol, 30 (6), 1357-67
PubMed 20065039

Centre for Molecular Biology and Neuroscience (CMBN)
PO Box 1105 Blindern, NO-0317 Oslo, Norway. Tel: +47 22851528. Fax: +47 22851488